The gap between wanting pizza at midnight and finding one that accommodates both gluten-free and vegan requirements has shrunk considerably in the past five years. A handful of Manhattan pizzerias now keep gluten-free crusts and plant-based toppings in stock well into the early morning, and most operate as walk-in spots rather than reservation-only restaurants. The challenge is knowing which ones actually stock both options and which close their kitchens before you arrive.
The Karpo app shows which pizzerias have gluten-free and vegan options available right now, with live kitchen hours and walk-in wait times at each location.
Artistic Pizza in Greenwich Village keeps gluten-free vegan pies in rotation until 4:00 AM on weekends
Artistic Pizza sits at 123 W 3rd St in Greenwich Village and runs Sunday through Thursday from 10:00 AM to 2:00 AM, extending to 4:00 AM Friday and Saturday. The menu lists vegan Beyond Pepperoni and a gluten-free vegan Hawaii Luau pie, putting it among the few places that explicitly combine both dietary tracks on a single order. The operation is walk-in or phone ordering, with no verified reservation platform.
The late-night window matters most here. A pizzeria that stays open until 4:00 AM on a weekend becomes the default answer when other kitchens have closed, and the fact that gluten-free and vegan options remain available through those hours is unusual. The storefront opens directly onto the sidewalk with bright interior lighting and a grab-and-go layout, so expect fast service rather than a long sit-down meal.
Nuovo York Pizza in the East Village offers 12-inch gluten-free pies but warns about cross-contact
Nuovo York Pizza operates at 105 E 9th St in the East Village, Monday through Thursday and Sunday from 11:00 AM to 3:00 AM, and Friday through Saturday until 4:30 AM. The kitchen serves 12-inch gluten-free pizzas and states that vegan options are also available. Walk-in or direct ordering is the standard approach, with no verified reservation system.
The venue explicitly notes that it is not celiac-safe because cross-contact with wheat flour is possible in the kitchen. That distinction is important if you have celiac disease rather than a preference-based gluten restriction. For those who can tolerate trace exposure, the East Village location and the 4:30 AM Friday and Saturday closing time make it a strong late-night option. The shop is narrow with a simple storefront and warm indoor lighting, fitting the dense streetscape that defines the neighborhood.
Green Oven Pizza in Hell's Kitchen runs until 3:00 AM every night with a wide vegan and gluten-free selection
Green Oven Pizza is at 707 9th Ave in Hell's Kitchen and operates daily from 10:00 AM to 3:00 AM. The kitchen is known for a wide variety of vegan and gluten-free pizzas, including plant-based protein options. The ordering model is walk-in or takeout-style, with no verified reservation platform.
The consistent 3:00 AM closing time across all seven days makes this the most reliable late-night address in the group. The post-theater window is especially useful, given the Hell's Kitchen location and the number of Broadway houses within a ten-minute walk. The storefront faces a busy avenue with strong indoor lighting and a fast-service counter layout, so expect a utilitarian experience rather than a cozy dining room.
&pizza on Broadway offers fast-casual customization with gluten-free crusts in a NoHo location
&pizza is at 740 Broadway on the NoHo and Greenwich Village edge, open Sunday through Thursday from 11:00 AM to 11:00 PM and Friday through Saturday until midnight. The location is documented as having gluten-free pizza options, and the chain's build-your-own format allows for vegan-friendly customization. Walk-in or fast-casual ordering is the standard method, with no verified reservation system.
The operational detail that matters most is the build-your-own format. This is better for quick custom orders than for a long dine-in meal, and the high-traffic Broadway storefront reinforces the grab-and-go expectation. The space is bright and modern with clean lines and visible prep areas, so you can watch your pizza being assembled. If you need specific toppings excluded or substituted, this format gives you the most control.
Kesté Pizza e Vino in the Financial District includes gluten-free and vegan options with a sit-down dining room
Kesté Pizza e Vino operates at 77 Fulton St in the Financial District. Hours are Sunday 11:30 AM to 10:00 PM, Monday through Thursday 11:30 AM to 3:30 PM and 4:30 PM to 10:00 PM, and Friday through Saturday 11:30 AM to 11:00 PM. The menu includes gluten-free pizzas plus vegetarian and vegan options, and reservations appear to be used, though the exact platform and lead time were not verified.
The split lunch-and-dinner schedule Monday through Thursday means there is a daily break in service, so arriving between 3:30 PM and 4:30 PM will find the doors closed even though the restaurant is otherwise open. This is a more polished sit-down pizzeria with a restaurant dining-room feel, softer lighting, and a fuller interior than a slice shop. If you want a longer meal with wine rather than a quick slice, this is the downtown option that accommodates that pace.
How to choose
Pick the place with the latest closing time if you need truly late-night pizza; Green Oven Pizza in Hell's Kitchen stays open until 3:00 AM every night, while Artistic Pizza and Nuovo York Pizza extend to 4:00 AM or 4:30 AM on weekends. Choose the spot that explicitly mentions gluten-free and vegan on the menu if cross-contact matters; Nuovo York Pizza warns that it is not celiac-safe, so if you have celiac disease rather than a preference, that venue should move to the bottom of your list. Use the neighborhood that is already on your route. These five are spread across Greenwich Village, the East Village, Hell's Kitchen, NoHo, and the Financial District, so the shortest walk is usually the best answer. The Karpo app shows live kitchen hours and current wait times at each location, which matters more at 2:00 AM than at noon.
One correction before you go
A common wrong assumption is that any gluten-free pizza is safe for celiac diners. The correct version is that some NYC pizzerias offer gluten-free crusts but still warn about cross-contact with wheat flour in the kitchen. Only places with explicit celiac-safe handling protocols should be treated as safe if you have celiac disease. Nuovo York Pizza, for example, offers gluten-free crusts but states that cross-contact is possible, which makes it suitable for preference-based gluten avoidance but not for medical necessity. Always ask about kitchen procedures if celiac safety is required.
Practical notes
Artistic Pizza is at 123 W 3rd St, New York, NY 10012, open Sunday through Thursday 10:00 AM to 2:00 AM and Friday through Saturday 10:00 AM to 4:00 AM, walk-in or phone ordering. Nuovo York Pizza is at 105 E 9th St, New York, NY 10003, open Monday through Thursday and Sunday 11:00 AM to 3:00 AM and Friday through Saturday 11:00 AM to 4:30 AM, walk-in or direct ordering. Green Oven Pizza is at 707 9th Ave, New York, NY 10019, open daily 10:00 AM to 3:00 AM, walk-in or takeout ordering. &pizza is at 740 Broadway, New York, NY 10003, open Sunday through Thursday 11:00 AM to 11:00 PM and Friday through Saturday 11:00 AM to midnight, walk-in or fast-casual ordering. Kesté Pizza e Vino is at 77 Fulton St, New York, NY 10038, open Sunday 11:30 AM to 10:00 PM, Monday through Thursday 11:30 AM to 3:30 PM and 4:30 PM to 10:00 PM, Friday through Saturday 11:30 AM to 11:00 PM, reservations appear to be used but platform details were not verified.
Tags: #PizzaNearMe #GlutenFreePizza #VeganPizza #GreenwichVillage #EastVillage #HellsKitchen #NoHo #FinancialDistrict #LateNightPizza #ArtisticPizza #NuovoYorkPizza #GreenOvenPizza #AndPizza #KestePizza #ManhattanPizza
Please drink responsibly. Must be of legal drinking age.
All trademarks are the property of their respective owners.
Ask Karpo first
Want to know which of these is actually open tonight, where the wait is shortest, and what changes on the day you go? Ask Karpo in the Karpo APP for the latest gluten free & vegan pizza updates, a booking plan that fits your timing, and a live route around New York City before you head out.
