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Neapolitan Pizza Near Me at San Matteo Upper East Side
Fabio and Ciro Casella's Upper East Side pizzeria serves Campanian pies, house mozzarella, panuozzi, and a deep regional menu.
San Matteo is a useful neapolitan pizza near me answer for the Upper East Side because the restaurant reaches beyond a short greatest-hits list. Brothers Fabio and Ciro Casella have served Campanian food in New York since 2010, and their dining room at 1559 Second Avenue combines true Neapolitan pizza with pasta, panuozzi, antipasti, and regional ingredients. The result is a neighborhood restaurant where a pizza specialist can study the crust while the rest of the table orders a broader Italian dinner. It is generous, family-friendly, and firmly tied to Salerno traditions.

The pizzeria sits on Second Avenue near East 81st Street, close to the Q train at 86th Street and buses running along the avenue. It is also a practical stop before or after the Metropolitan Museum of Art, though the walk crosses several avenues and should be treated as part of the outing. Approaching from Central Park, pass the residential blocks eastward and arrive hungry. Second Avenue is busy at dinner, so transit is easier than circling for a curb space, particularly on Friday and Saturday nights.
The Casella brothers describe themselves as the owners and souls of the restaurant, and the official story emphasizes Italian, Campanian, and Salerno products. That identity appears in house mozzarella, buffalo cheese, Sicilian anchovies, broccoli rabe, smoked meats, and the panuozzo tradition. San Matteo does not present Naples as a single red-sauce formula. Its menu traces the wider region through stuffed bread, white pies, pasta, and seafood. The best meal therefore includes one classic pizza and one order that would be difficult to reproduce at a generic neighborhood shop.
The $20 Margherita uses tomato sauce, homemade mozzarella, and fresh basil. It is the cleanest test of San Matteo's house cheese and oven. The $18 Napoletana, despite the name, is the cheeseless combination of tomato, basil, garlic, and dried oregano, while the $20 Marinara adds capers, black olives, and Sicilian anchovies. Read the descriptions rather than assuming every restaurant uses identical names. Here, Napoletana is the simpler vegan-friendly red pie, and Marinara is the salty, anchovy-laden option.
For a fuller classic, the $24 Regina Margherita adds cherry tomatoes, buffalo mozzarella, and Parmigiano Reggiano to tomato and basil. It is juicier and tangier than the standard Margherita because both fresh tomatoes and buffalo milk cheese carry more moisture. Share the two only with a larger group; for a couple, choose one based on appetite. The standard pie emphasizes the restaurant's homemade mozzarella, while Regina feels more luxurious and is better followed by a bitter salad or vegetable appetizer rather than another dairy-heavy course.
The $24 Diavola combines tomato, homemade mozzarella, basil, spicy sopressata, and Parmigiano Reggiano. Its heat is driven by cured meat rather than a heavy chili sauce, so the tomato remains recognizable. A more complex red option is the $25 Prosciutto and Bufala with buffalo mozzarella, basil, Parma ham, and Parmigiano. Do not order both for two people; the cured-meat overlap becomes repetitive. Pair Diavola with a white vegetable pizza, or match Prosciutto and Bufala with the spare Napoletana for a clearer contrast.
San Matteo's white pies reveal the menu's regional personality. The $25 Salsiccia and Friarieli joins homemade mozzarella, sausage, and broccoli rabe, a classic Campanian combination whose bitterness keeps the pork from feeling heavy. The $23 Cacio e Pepe uses dry-cured pancetta, caciocavallo, and cracked pepper, translating the pasta flavor into a pizza without tomato. The $25 Minala layers Amalfi red and yellow cherry tomatoes, basil, olive oil, mozzarella, and burrata. Each pie makes sense for a different table, so choose one theme instead of collecting toppings.
Panuozzi are the order that distinguishes a return visit. These long sandwiches are made from pizza dough and filled after baking, connecting the pizzeria to a Campanian street-food tradition beyond round pies. The menu also includes a $24 pizza roll filled with prosciutto di Parma, buffalo mozzarella, cherry tomatoes, and baby arugula, finished with balsamic glaze. These formats are easier to share at lunch than at a crowded dinner table. If your first meal is pizza-focused, remember the bread section for the next visit rather than forcing every specialty into one sitting.
Reservations are encouraged through the restaurant's online system. Monday through Thursday service begins at 4 pm and runs to 10 pm; Friday and Saturday start at noon and continue to 11 pm; Sunday runs noon to 10 pm. The weekend noon opening creates the calmest family strategy and works well with nearby museums or Central Park. At dinner, book ahead and have the full party arrive together. The menu is broad enough that indecision, not lack of choice, is the greater threat to a relaxed meal.
The dining room has the energy of an established neighborhood Italian restaurant rather than a minimalist pizza laboratory. Bread baskets, pasta plates, wine, and pizza all circulate through the room. Keep an order coherent by choosing one appetizer, two contrasting pies, and perhaps pasta only for a larger table. Because the pizzas use soft centers and house cheese, eat them first. Pasta can tolerate a few minutes on the table; a blistered crust cannot. Ask the server to stagger courses if your group is mixing categories.
Make the surrounding Upper East Side part of the plan. Walk west to the Metropolitan Museum, continue north or south through Central Park, or stay east and browse Yorkville's smaller bars, cafes, and specialty shops. Carl Schurz Park is a longer walk toward the East River and works well before an early dinner. A neighborhood route helps distinguish San Matteo from destination pizzerias downtown: this is a place woven into errands, museum days, family gatherings, and residential evenings rather than a restaurant that demands the entire day's attention.
Practical Notes: San Matteo Pizzeria e Cucina is at 1559 2nd Ave, New York, NY 10028. Hours are 4 pm–10 pm Monday through Thursday, 12 pm–11 pm Friday and Saturday, and 12 pm–10 pm Sunday. Online reservations, ordering, catering, and private-party inquiries are available. The restaurant serves whole pizzas and a full menu. Second Avenue buses and the Q train reduce the uncertainty of parking, and weekend lunch is the easiest window for families.
A strong first order for three people is the $18 Napoletana, the $25 Salsiccia and Friarieli, and the $24 Regina Margherita. That set moves from cheeseless tomato and garlic to sausage with bitter greens, then buffalo mozzarella and cherry tomatoes. Two diners should remove one pie and add an appetizer only if necessary. The goal is not maximum variety; it is a sequence in which each crust arrives hot and each topping profile remains distinct. Use Karpo in the Karpo APP to fit the meal around a museum ticket or park walk.
San Matteo suits diners who want genuine Neapolitan technique without asking the entire table to follow a narrow pizza-only agenda. The Casella brothers' Campanian focus gives the restaurant a clear point of view, while the schedule and menu make it approachable for Upper East Side routines. The strongest choices are not necessarily the most elaborate: house mozzarella on Margherita, garlic and oregano on Napoletana, or sausage and friarielli on a white base each tell a regional story. Order selectively, notice the bread, and leave a reason to return for panuozzi.
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